Interactor 1: TRXR1 (O89049)
Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (NADPH-dependent thioredoxin reductase) (Peroxidase TXNRD1) (EC 1.11.1.2) (Thioredoxin reductase TR1)
Gene: Txnrd1

Interactor 2: TRXR1 (O89049)
Thioredoxin reductase 1, cytoplasmic (TR) (EC 1.8.1.9) (NADPH-dependent thioredoxin reductase) (Peroxidase TXNRD1) (EC 1.11.1.2) (Thioredoxin reductase TR1)
Gene: Txnrd1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 11481439
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pyr_redox_2~Pyr_redox_2, Pyr_redox_2~Pyr_redox_dim, Pyr_redox_dim~Pyr_redox_dim
Common GO terms GO:0001707 - mesoderm formation
GO:0004362 - glutathione-disulfide reductase (NADPH) activity
GO:0004791 - thioredoxin-disulfide reductase (NADPH) activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 26 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 499
Rn

1 499
+ Hs
+ Hs
+ Dm
+ Dm
+ At
+ Sp
+ Ec
+ Sc
+ Ec
+ Mp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024