Interactor 1: CASP8 (O89110)
Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
Gene: CASP8

Interactor 2: TR10B (Q9QZM4)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (MK) (CD antigen CD262)
Gene: Tnfrsf10b

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21251615
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 480
Mm

1 381
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024