HitPredict

Interactor 1: SMC1A (O93308)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1A) (xSMC1)
Gene: SMC1A

Interactor 2: PD5AA (Q4QXM3)
Sister chromatid cohesion protein PDS5 homolog A-A
Gene: pds5a-a

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15855230
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006281 - DNA repair GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1232 Xl			1 1323
+	Xl
		292729 SMC1A_XENLA (1-1232): 1.83e-119: 402: 100.00		PD5AB_XENLA (1-1323): 0: 1757: 99.62
+	Hs
		1057273 SMC1A_HUMAN (1-1232): 1.59e-122: 411: 93.91		PDS5A_HUMAN (1-1323): 0: 1686: 86.57
+	Mm
		93884 SMC1A_MOUSE (1-1232): 8.04e-123: 411: 93.99		E9QPI5_MOUSE (1-1323): 0: 1653: 86.63
+	Mm
		1149127 SMC1A_MOUSE (1-1232): 8.04e-123: 411: 93.99		PDS5A_MOUSE (1-1323): 0: 1633: 86.33
+	Xl
		1117310 Q8AW91_XENLA (3-1225): 7.38e-75: 273: 17.03		PD5AB_XENLA (1-1323): 0: 1757: 99.62
+	Xl
		292739 SMC3_XENLA (3-1225): 3.1e-74: 271: 16.87		PD5AA_XENLA (1-1323): 0: 1759: 100.00
+	Xl
		292728 SMC1A_XENLA (1-1232): 1.83e-119: 402: 100.00		PD5BA_XENLA (5-1317): 0: 1576: 66.18
+	Hs
		1057405 SMC1A_HUMAN (1-1232): 1.59e-122: 411: 93.91		PDS5B_HUMAN (5-1313): 0: 1566: 66.72
+	Mm
		1118817 SMC1A_MOUSE (1-1232): 8.04e-123: 411: 93.99		PDS5B_MOUSE (5-1317): 0: 1560: 66.27
+	Hs
		1100586 SMC3_HUMAN (3-1212): 3.33e-75: 275: 17.70		PDS5A_HUMAN (1-1323): 0: 1686: 86.57
+	Mm
		93885 SMC3_MOUSE (3-1212): 2.8e-75: 275: 17.70		E9QPI5_MOUSE (1-1323): 0: 1653: 86.63
+	Xl
		292740 SMC3_XENLA (3-1225): 3.1e-74: 271: 16.87		PD5BB_XENLA (5-1317): 0: 1592: 66.62
+	Xl
		1115499 Q8AW91_XENLA (3-1225): 7.38e-75: 273: 17.03		PD5BA_XENLA (5-1317): 0: 1576: 66.18
+	Xl
		292738 SMC3_XENLA (3-1225): 3.1e-74: 271: 16.87		PD5BA_XENLA (5-1317): 0: 1576: 66.18
+	Hs
		1345702 SMC3_HUMAN (3-1212): 3.33e-75: 275: 17.70		PDS5B_HUMAN (5-1313): 0: 1566: 66.72
+	Sp
		293288 SMC1_SCHPO (1-1225): 1.13e-74: 273: 32.45		PDS5_SCHPO (26-1152): 0: 905: 21.56
+	Sp
		193880 SMC3_SCHPO (3-1215): 1.63e-68: 254: 16.16		PDS5_SCHPO (26-1152): 0: 905: 21.56
+	Sc
		810772 SMC3_YEAST (3-1215): 9.56e-77: 279: 18.45		PDS5_YEAST (28-1152): 0: 851: 18.14
+	Sc
		700799 SMC1_YEAST (1-1225): 2.26e-69: 257: 26.95		PDS5_YEAST (28-1152): 0: 851: 18.14
+	Hs
		69118 SMC1A_HUMAN (1-1232): 1.59e-122: 411: 93.91		A9IYQ1_HUMAN (1049-1313): 6.22e-61: 213: 29.33