HitPredict

Interactor 1: SN114 (O94316)
Pre-mRNA-splicing factor cwf10 (114 kDa U5 small nuclear ribonucleoprotein component homolog) (Complexed with cdc5 protein 10)
Gene: cwf10

Interactor 2: CWC2 (P87126)
Pre-mRNA-splicing factor cwf2 (Complexed with cdc5 protein 2) (Pre-mRNA-processing protein 3)
Gene: cwf2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	21386897, 24014766, 24442611
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000974 - Prp19 complex GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0071007 - U2-type catalytic step 2 spliceosome GO:0071014 - post-mRNA release spliceosomal complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 984 Sp			1 388
+	Hs
		1064773 U5S1_HUMAN (2-983): 0: 1012: 54.07		RBM22_HUMAN (84-275): 9.1e-72: 232: 22.82
+	Hs
		1031337 U5S1_HUMAN (2-983): 0: 1012: 54.07		PABP4_HUMAN (2-292): 2.87e-49: 177: 14.62
+	Hs
		516526 U5S1_HUMAN (2-983): 0: 1012: 54.07		PABP1_HUMAN (2-307): 5.91e-49: 176: 12.93
+	Sp
		292934 SN114_SCHPO (1-984): 0: 985: 100.00		PABP_SCHPO (55-387): 8.33e-46: 168: 10.17
+	Sc
		731784 SN114_YEAST (1-981): 0: 672: 33.40		CWC2_YEAST (46-295): 4.28e-58: 194: 36.86
+	Sc
		731755 SN114_YEAST (1-981): 0: 672: 33.40		NAM8_YEAST (33-248): 7.51e-24: 104: 12.22