HitPredict

Interactor 1: VPS20 (O94318)
Vacuolar protein sorting-associated protein 20
Gene: VPS20

Interactor 2: SNF8 (O94663)
Vacuolar-sorting protein dot2 (Defective organization of telomere protein 2) (ELL-associated protein of 30 kDa homolog dot2)
Gene: dot2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	26771498, 23695164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0045324 - late endosome to vacuole transport
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 226 Sp			1 252
+	Hs
		1291667 CHMP6_HUMAN (3-180): 2.75e-26: 102: 32.02		SNF8_HUMAN (2-250): 3.53e-117: 337: 34.52
+	Ce
		1089992 Q9BL60_CAEEL (4-198): 5.58e-26: 101: 26.53		Q18258_CAEEL (2-243): 5.5e-109: 317: 31.71
+	Sc
		764907 SNF7_YEAST (9-222): 4.51e-31: 116: 22.17		SNF8_YEAST (3-240): 5.35e-98: 287: 35.57
+	Sc
		979220 VPS20_YEAST (1-208): 3.14e-28: 107: 23.96		SNF8_YEAST (3-240): 5.35e-98: 287: 35.57
+	Sc
		810991 YJE9_YEAST (8-140): 2.88e-23: 98.7: 20.00		SNF8_YEAST (3-240): 5.35e-98: 287: 35.57