HitPredict

Interactor 1: SMC1 (O94383)
Structural maintenance of chromosomes protein 1 (Chromosome segregation protein smc1) (Cohesin complex subunit psm1)
Gene: psm1

Interactor 2: REC11 (Q92380)
Meiotic recombination protein rec11
Gene: REC11

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29898918, 25993311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0007062 - sister chromatid cohesion GO:0008278 - cohesin complex GO:0030893 - meiotic cohesin complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1228 Sp			1 923
+	Mm
		193223 SMC1A_MOUSE (1-1226): 1.97e-93: 328: 32.50		STAG2_MOUSE (3-710): 0: 688: 16.00
+	Mm
		193221 SMC1B_MOUSE (1-1226): 8.64e-91: 321: 29.55		STAG2_MOUSE (3-710): 0: 688: 16.00
+	Hs
		1057313 SMC1A_HUMAN (1-1226): 2.19e-93: 328: 32.50		STAG2_HUMAN (3-710): 0: 680: 15.86
+	Hs
		1057335 SMC1A_HUMAN (1-1226): 2.19e-93: 328: 32.50		STAG1_HUMAN (7-667): 0: 674: 17.71
+	Xl
		292732 SMC1A_XENLA (1-1226): 1.01e-88: 315: 32.82		Q5XGV2_XENLA (8-710): 0: 686: 15.43
+	Mm
		1265314 SMC1B_MOUSE (1-1226): 8.64e-91: 321: 29.55		STAG1_MOUSE (7-667): 0: 673: 17.57
+	Xl
		292734 SMC1A_XENLA (1-1226): 1.01e-88: 315: 32.82		STAG2_XENLA (64-710): 0: 676: 15.67
+	Xl
		292735 SMC1A_XENLA (1-1226): 1.01e-88: 315: 32.82		STAG1_XENLA (5-661): 0: 652: 17.37
+	Mm
		193224 SMC3_MOUSE (3-1225): 2.53e-72: 266: 14.47		STAG2_MOUSE (3-710): 0: 688: 16.00
+	Xl
		1140122 Q8AW91_XENLA (3-1225): 2.07e-70: 260: 14.62		Q5XGV2_XENLA (8-710): 0: 686: 15.43
+	Hs
		1232591 SMC3_HUMAN (3-1225): 3.12e-72: 265: 14.47		STAG2_HUMAN (3-710): 0: 680: 15.86
+	Hs
		1261592 SMC3_HUMAN (3-1225): 3.12e-72: 265: 14.47		STAG1_HUMAN (7-667): 0: 674: 17.71
+	Xl
		1206293 Q8AW91_XENLA (3-1225): 2.07e-70: 260: 14.62		STAG2_XENLA (64-710): 0: 676: 15.67
+	Hs
		1057419 SMC1A_HUMAN (1-1226): 2.19e-93: 328: 32.50		STAG3_HUMAN (6-763): 0: 594: 13.69
+	Mm
		251066 SMC1B_MOUSE (1-1226): 8.64e-91: 321: 29.55		STAG3_MOUSE (7-754): 1.47e-179: 554: 13.86
+	Hs
		1355962 SMC3_HUMAN (3-1225): 3.12e-72: 265: 14.47		STAG3_HUMAN (6-763): 0: 594: 13.69
+	Mm
		251067 SMC3_MOUSE (3-1225): 2.53e-72: 266: 14.47		STAG3_MOUSE (7-754): 1.47e-179: 554: 13.86
+	Sp
		143296 SMC1_SCHPO (1-1228): 1.35e-99: 346: 100.00		SCC3_SCHPO (67-716): 1.17e-145: 458: 20.60
+	Dm
		1362841 Q9VCD8_DROME (3-1221): 1.51e-76: 279: 30.07		Q9VM62_DROME (29-733): 1.18e-163: 510: 13.32
+	Sc
		700774 SMC1_YEAST (1-1228): 2.12e-79: 287: 33.01		SCC3_YEAST (42-431): 5.89e-96: 329: 18.61