HitPredict

Interactor 1: CSN5 (O94454)
COP9 signalosome complex subunit 5 (EC 3.4.-.-)
Gene: CSN5

Interactor 2: CSN2 (Q9HFR0)
COP9 signalosome complex subunit 2 (CSN complex subunit 2) (SGN2)
Gene: CSN2

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11854407
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005634 - nucleus GO:0005829 - cytosol GO:0008180 - COP9 signalosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 299 Sp			1 437
+	Dm
		1277039 CSN5_DROME (3-299): 1.34e-105: 312: 40.00		CSN2_DROME (13-435): 2.02e-132: 390: 44.10
+	Mm
		193516 CSN5_MOUSE (4-299): 7.67e-96: 287: 38.85		CSN2_MOUSE (1-435): 5.12e-140: 409: 46.10
+	Hs
		897288 CSN5_HUMAN (4-299): 1.22e-95: 287: 38.85		CSN2_HUMAN (1-435): 5.12e-140: 409: 46.10
+	At
		1227249 CSN5A_ARATH (2-298): 3.05e-95: 287: 38.05		CSN2_ARATH (9-437): 3.41e-130: 384: 45.48
+	At
		1258867 CSN5B_ARATH (2-298): 5.26e-94: 284: 37.74		CSN2_ARATH (9-437): 3.41e-130: 384: 45.48
+	An
		1124314 CSN5_EMENI (1-298): 6.34e-91: 275: 35.67		CSN2_EMENI (2-437): 5.24e-129: 384: 44.27
+	Ce
		136314 CSN5_CAEEL (5-292): 3.58e-90: 274: 39.24		CSN2_CAEEL (14-425): 1.92e-122: 366: 42.55
+	Hs
		121709 PSMD7_HUMAN (32-298): 2.77e-70: 222: 14.03		PSD11_HUMAN (34-434): 1.17e-110: 333: 18.54
+	Dm
		1180711 PSDE_DROME (18-293): 1.06e-73: 230: 27.49		PSD11_DROME (29-434): 2.16e-104: 317: 16.71
+	Hs
		849202 PSMD7_HUMAN (32-298): 2.77e-70: 222: 14.03		PSMD6_HUMAN (102-436): 5.27e-104: 315: 12.43
+	Hs
		1024199 CSN5_HUMAN (4-299): 1.22e-95: 287: 38.85		CSN1_HUMAN (117-425): 8.13e-73: 238: 10.17
+	Dm
		1358521 PSDE_DROME (18-293): 1.06e-73: 230: 27.49		PSMD6_DROME (96-436): 5.27e-95: 292: 12.47
+	At
		799472 CSN5A_ARATH (2-298): 3.05e-95: 287: 38.05		CSN1_ARATH (142-429): 8.56e-72: 234: 16.55
+	Mm
		102340 CSN5_MOUSE (4-299): 7.67e-96: 287: 38.85		G3UXW9_MOUSE (112-425): 1.46e-69: 231: 11.23
+	At
		799480 CSN5B_ARATH (2-298): 5.26e-94: 284: 37.74		CSN1_ARATH (142-429): 8.56e-72: 234: 16.55
+	Mm
		193526 CSN5_MOUSE (4-299): 7.67e-96: 287: 38.85		CSN1_MOUSE (112-425): 9.75e-69: 227: 11.23
+	Hs
		1272576 CSN5_HUMAN (4-299): 1.22e-95: 287: 38.85		CSN4_HUMAN (73-411): 2.86e-69: 226: 13.52
+	Mm
		193509 CSN5_MOUSE (4-299): 7.67e-96: 287: 38.85		CSN4_MOUSE (73-411): 3.22e-69: 226: 13.80
+	An
		1124330 CSN5_EMENI (1-298): 6.34e-91: 275: 35.67		CSN1_EMENI (102-430): 8.83e-61: 207: 13.10
+	Ce
		954225 CSN5_CAEEL (5-292): 3.58e-90: 274: 39.24		CSN1_CAEEL (281-436): 6.29e-32: 129: 20.83