HitPredict

Interactor 1: SRK1 (O94547)
Serine/threonine-protein kinase srk1 (EC 2.7.11.1) (Sty1-regulated kinase 1)
Gene: SRK1

Interactor 2: HOG1 (Q09892)
Mitogen-activated protein kinase sty1 (MAP kinase sty1) (EC 2.7.11.24) (MAP kinase spc1)
Gene: sty1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.914

The method score is based on:

Property Details
Experiments 12080074, 12589433, 18065650, 18272791
Identification Methods affinity chromatography technology, enzymatic study, pull down, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0010515 - negative regulation of induction of conjugation with cellular fusion
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 580
Sp

1 349
+ Sp
+ At
+ At
+ At
+ At
+ At
+ Sc
+ Mm
+ Hs
+ At
+ At
+ Hs
+ At
+ Sc
+ At
+ At
+ At
+ At
+ At
+ Rn

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Last updated: 15 Jul 2024