HitPredict

Interactor 1: PSA2 (O94579)
Probable proteasome subunit alpha type-2
Gene: pre8

Interactor 2: PSA3 (Q09682)
Probable proteasome subunit alpha type-3
Gene: SPAC13C5.01c

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22307589
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019773 - proteasome core complex, alpha-subunit complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Sp			1 248
+	Dm
		574014 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSA4_DROME (1-243): 3.36e-94: 278: 53.04
+	Hs
		637494 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62
+	Dm
		771303 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSA5_DROME (1-242): 1.59e-91: 271: 32.80
+	Hs
		637325 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSA1_HUMAN (1-248): 6.52e-102: 298: 31.62
+	Hs
		638067 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSA4_HUMAN (1-238): 7.96e-98: 288: 53.56
+	Ce
		1099869 PSA2_CAEEL (1-242): 2.15e-99: 290: 55.33		PSA7_CAEEL (4-239): 3.95e-91: 270: 34.03
+	Ce
		1278560 PSA5_CAEEL (3-245): 1.99e-98: 288: 35.22		PSA7_CAEEL (4-239): 3.95e-91: 270: 34.03
+	Ce
		1278563 PSA7_CAEEL (3-245): 4.45e-93: 275: 32.52		PSA4_CAEEL (1-238): 1.84e-95: 281: 53.78
+	Hs
		156328 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSA7_HUMAN (4-239): 1.01e-94: 279: 37.40
+	Hs
		156230 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSA7_HUMAN (4-239): 1.01e-94: 279: 37.40
+	Ce
		1278559 PSA7_CAEEL (3-245): 4.45e-93: 275: 32.52		PSA7_CAEEL (4-239): 3.95e-91: 270: 34.03
+	Hs
		656189 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSA6_HUMAN (2-244): 1.18e-91: 271: 31.71
+	Hs
		656276 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSA5_HUMAN (1-241): 5.01e-90: 267: 35.63
+	Hs
		656149 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSA5_HUMAN (1-241): 5.01e-90: 267: 35.63
+	Hs
		108927 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		H0YKT8_HUMAN (25-201): 4.46e-67: 207: 52.81
+	Ce
		1099867 PSA2_CAEEL (1-242): 2.15e-99: 290: 55.33		PSA2_CAEEL (1-201): 1.44e-42: 146: 38.42
+	Hs
		637719 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSA2_HUMAN (3-211): 1.5e-46: 156: 39.71
+	Hs
		637631 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSA2_HUMAN (3-211): 1.5e-46: 156: 39.71