HitPredict

Interactor 1: PSA2 (O94579)
Probable proteasome subunit alpha type-2
Gene: pre8

Interactor 2: PSB3 (Q9Y7T8)
Probable proteasome subunit beta type-3
Gene: pup3

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24938783
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome, Proteasome~Proteasome_A_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Sp			1 204
+	Dm
		771285 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSB1_DROME (2-204): 1.88e-75: 228: 27.10
+	Dm
		771294 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		Q7K148_DROME (6-204): 9.64e-68: 210: 21.11
+	Dm
		771328 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSB3_DROME (1-204): 1.62e-67: 207: 53.17
+	Dm
		184454 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		O17311_DROME (3-196): 7.17e-66: 205: 19.07
+	Dm
		771302 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		Q8T8V8_DROME (6-195): 3.45e-65: 204: 17.90
+	Dm
		771303 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSA5_DROME (8-204): 3.85e-65: 202: 15.39
+	Ce
		1099874 PSA2_CAEEL (1-242): 2.15e-99: 290: 55.33		PBS5_CAEEL (2-196): 5.47e-65: 203: 23.76
+	Af
		191426 PSA_ARCFU (4-244): 5.64e-95: 280: 39.83		PSB_ARCFU (1-204): 1.86e-69: 212: 25.60
+	Mt
		191406 PSA_METTH (2-245): 4.32e-97: 285: 38.12		PSB_METTH (7-203): 5.13e-67: 206: 22.84
+	Mm
		1154361 PSA_METMP (2-245): 9.83e-95: 280: 36.48		PSB_METMP (7-204): 3.84e-68: 209: 22.73
+	Ph
		223381 PSA_PYRHO (3-243): 7.43e-98: 287: 42.74		PSB1_PYRHO (5-201): 1.78e-63: 196: 24.24
+	Sp
		293714 PSA2_SCHPO (1-245): 1.89e-95: 281: 100.00		PSA3_SCHPO (1-199): 1.2e-64: 201: 12.81
+	Sp
		675393 PSA5_SCHPO (3-244): 8.14e-93: 274: 33.07		PSB5_SCHPO (6-196): 9.4e-66: 204: 18.85
+	Hs
		594591 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSB1_HUMAN (2-204): 1.08e-64: 201: 24.06
+	Hs
		656276 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSA5_HUMAN (8-204): 7.12e-65: 201: 13.11
+	Hs
		594455 PSA5_HUMAN (3-245): 1.42e-92: 273: 34.27		PSB1_HUMAN (2-204): 1.08e-64: 201: 24.06
+	Hs
		832023 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSB3_HUMAN (1-204): 5.32e-65: 200: 56.10
+	Hs
		656127 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSB9_HUMAN (6-203): 6.94e-64: 198: 22.73
+	Dm
		47598 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		A0AQH0_DROME (7-199): 3.73e-48: 158: 20.73
+	Hs
		656629 PSMA8_HUMAN (1-243): 1.09e-92: 274: 35.32		PSB6_HUMAN (7-203): 3.06e-50: 164: 18.27