HitPredict

Interactor 1: TTI1 (O94600)
TEL2-interacting protein 1
Gene: TTI1

Interactor 2: TOR2 (Q9Y7K2)
Serine/threonine-protein kinase tor2 (EC 2.7.11.1) (Phosphatidylinositol kinase homolog tor2) (Target of rapamycin kinase 2)
Gene: TOR2

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	18076573, 34686329, 31748520
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1098 Sp			1 2337
+	Sp
		145535 TTI1_SCHPO (1-1098): 0: 1516: 100.00		TOR1_SCHPO (1-2337): 0: 1767: 52.05
+	Sc
		715177 TTI1_YEAST (49-979): 0: 914: 19.60		TOR1_YEAST (2-2337): 0: 1736: 47.84
+	Dm
		1366743 Q9VH80_DROME (142-928): 0: 784: 15.82		TOR_DROME (2-2337): 0: 1583: 39.66
+	Sp
		293730 TTI1_SCHPO (1-1098): 0: 1516: 100.00		TRA1_SCHPO (3-2336): 0: 795: 14.14
+	Sp
		293728 TTI1_SCHPO (1-1098): 0: 1516: 100.00		YAMB_SCHPO (466-2336): 0: 752: 13.67
+	Sp
		293727 TTI1_SCHPO (1-1098): 0: 1516: 100.00		RAD3_SCHPO (426-2337): 0: 707: 15.65
+	Sp
		251726 TTI1_SCHPO (1-1098): 0: 1516: 100.00		ATM_SCHPO (1066-2336): 4e-153: 534: 17.96
+	Hs
		195892 TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24		MTOR_HUMAN (2-2337): 0: 1603: 41.79
+	At
		96186 F4IDJ4_ARATH (569-927): 1.72e-88: 313: 16.17		TOR_ARATH (2-2337): 0: 1662: 41.64
+	Sc
		732564 TTI1_YEAST (49-979): 0: 914: 19.60		TRA1_YEAST (16-2337): 0: 737: 13.02
+	Dm
		1211951 Q9VH80_DROME (142-928): 0: 784: 15.82		TRA1_DROME (61-2336): 0: 812: 13.34
+	Hs
		195907 TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24		ATR_HUMAN (169-2336): 0: 809: 15.92
+	Hs
		195955 TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24		TRRAP_HUMAN (37-2336): 0: 781: 13.48
+	Hs
		195905 TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24		ATM_HUMAN (214-2336): 0: 779: 15.28
+	Hs
		195901 TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24		PRKDC_HUMAN (590-2336): 0: 687: 15.78
+	Hs
		195935 TTI1_HUMAN (50-919): 4.64e-121: 400: 18.24		SMG1_HUMAN (1620-2315): 4.67e-109: 393: 21.65