HitPredict

Interactor 1: UBA1 (O94609)
Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45) (Poly(A)+ RNA transport protein 3)
Gene: ptr3

Interactor 2: UBC2 (P23566)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (RAD6 homolog) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: rhp6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	23416107, 28162934
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1012 Sp			1 151
+	Hs
		607190 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D4_HUMAN (5-149): 2.31e-81: 238: 40.69
+	Hs
		607026 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D1_HUMAN (5-149): 4.92e-81: 237: 40.00
+	Hs
		607050 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D2_HUMAN (5-149): 5.73e-81: 236: 39.31
+	Hs
		607039 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D3_HUMAN (5-149): 2.07e-79: 233: 39.31
+	Hs
		607136 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2E2_HUMAN (3-150): 1.49e-76: 227: 35.14
+	Hs
		607129 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2E3_HUMAN (3-150): 5.25e-76: 226: 35.14
+	Hs
		607023 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UBE2A_HUMAN (1-149): 1.14e-75: 223: 72.48
+	Hs
		607028 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2E1_HUMAN (3-150): 1.15e-74: 222: 35.14
+	Hs
		607054 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UBE2B_HUMAN (1-149): 6.32e-75: 221: 71.81
+	Sp
		293848 UBA1_SCHPO (1-1012): 0: 1193: 100.00		UBC4_SCHPO (5-149): 8.89e-80: 233: 39.31
+	Sc
		549788 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC4_YEAST (1-149): 1.57e-80: 235: 37.58
+	Sc
		410211 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC2_YEAST (1-150): 1.4e-73: 219: 77.33
+	Hs
		607038 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2G2_HUMAN (1-148): 3.48e-36: 124: 37.65
+	Hs
		48104 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2D1_HUMAN (5-149): 4.92e-81: 237: 40.00
+	Hs
		48107 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2D2_HUMAN (5-149): 5.73e-81: 236: 39.31
+	Hs
		48106 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2D3_HUMAN (5-149): 2.07e-79: 233: 39.31
+	Sc
		608719 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC7_YEAST (1-148): 2.02e-36: 124: 38.89
+	Hs
		782203 UBA7_HUMAN (7-1012): 0: 981: 37.85		UB2E1_HUMAN (3-150): 1.15e-74: 222: 35.14
+	Hs
		48105 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2G2_HUMAN (1-148): 3.48e-36: 124: 37.65
+	Sc
		854609 UBA2_YEAST (409-1009): 1.22e-78: 271: 21.95		UBC7_YEAST (1-148): 2.02e-36: 124: 38.89