HitPredict

Interactor 1: UBA1 (O94609)
Ubiquitin-activating enzyme E1 1 (EC 6.2.1.45) (Poly(A)+ RNA transport protein 3)
Gene: ptr3

Interactor 2: UBC14 (Q9UTN8)
Ubiquitin-conjugating enzyme E2 14 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 14) (Ubiquitin carrier protein 14) (Ubiquitin-protein ligase 14)
Gene: UBC14

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	23416107, 28162934
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	E1_UFD~UQ_con, ThiF~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1012 Sp			1 155
+	Hs
		607190 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D4_HUMAN (7-154): 1.65e-81: 238: 44.60
+	Hs
		607026 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D1_HUMAN (7-154): 1.21e-80: 236: 45.27
+	Hs
		607050 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D2_HUMAN (7-154): 1.72e-80: 235: 45.27
+	Hs
		607039 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2D3_HUMAN (7-154): 3.63e-79: 232: 45.27
+	Hs
		607136 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2E2_HUMAN (2-153): 3.77e-74: 221: 41.45
+	Hs
		607129 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2E3_HUMAN (2-153): 1.53e-73: 220: 41.45
+	Hs
		607028 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2E1_HUMAN (2-153): 1.38e-72: 217: 40.79
+	Hs
		607023 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UBE2A_HUMAN (4-151): 3.23e-71: 212: 31.08
+	Sp
		293848 UBA1_SCHPO (1-1012): 0: 1193: 100.00		UBC4_SCHPO (7-153): 3.52e-78: 230: 46.26
+	Hs
		607054 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UBE2B_HUMAN (4-151): 1.95e-70: 210: 31.08
+	Hs
		607042 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UBE2N_HUMAN (9-155): 1.78e-68: 205: 37.42
+	Sc
		549788 UBA1_YEAST (2-1012): 0: 1122: 58.44		UBC4_YEAST (7-153): 3.15e-78: 230: 49.66
+	Hs
		607057 UBA1_HUMAN (1-1012): 0: 1212: 52.97		UB2L3_HUMAN (7-154): 7.39e-31: 110: 36.91
+	Sp
		142467 UBA1_SCHPO (1-1012): 0: 1193: 100.00		UBC13_SCHPO (10-153): 4.42e-32: 113: 39.58
+	Dm
		715098 Q8T0L3_DROME (2-1012): 0: 1100: 50.74		UBE2N_DROME (6-153): 8.49e-69: 206: 36.49
+	Hs
		48104 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2D1_HUMAN (7-154): 1.21e-80: 236: 45.27
+	Hs
		48107 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2D2_HUMAN (7-154): 1.72e-80: 235: 45.27
+	Hs
		48106 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2D3_HUMAN (7-154): 3.63e-79: 232: 45.27
+	Hs
		782203 UBA7_HUMAN (7-1012): 0: 981: 37.85		UB2E1_HUMAN (2-153): 1.38e-72: 217: 40.79
+	Hs
		48108 UBA6_HUMAN (2-1012): 0: 1038: 39.69		UB2L3_HUMAN (7-154): 7.39e-31: 110: 36.91