HitPredict

Interactor 1: TFB3 (O94684)
RNA polymerase II transcription factor B subunit 3 (CDK-activating kinase assembly factor MAT1 homolog) (RING finger protein pmh1) (RNA polymerase II transcription factor B 38 kDa subunit) (RNA polymerase II transcription factor B p38 subunit)
Gene: pmh1

Interactor 2: CRK1 (Q12126)
Serine/threonine-protein kinase crk1 (EC 2.7.11.23) (Mitotic catastrophe suppressor 6)
Gene: CRK1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.819

The method score is based on:

Property Details
Experiments 14534314, 15555586
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MAT1~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005675 - transcription factor TFIIH holo complex
GO:0005829 - cytosol
GO:0006367 - transcription initiation at RNA polymerase II promoter
GO:0016251 - RNA polymerase II general transcription initiation factor activity
and 1 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 318
Sp

1 335
+ Hs
+ Hs
+ Dm
+ Sc
+ At
+ At
+ At

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Last updated: 15 Jul 2024