HitPredict

Interactor 1: SEM1 (O94742)
26S proteasome complex subunit SEM1
Gene: SEM1

Interactor 2: THP1 (Q08231)
Nuclear mRNA export protein THP1 (Bud site selection protein 29)
Gene: THP1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.916

Property	Details
Experiments	22343721, 24824343, 19061648, 19289793, 23643786
Identification Methods	pull down, tandem affinity purification, affinity chromatography technology, x-ray crystallography
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DSS1_SEM1~PCI
Common GO terms	GO:0006406 - mRNA export from nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0070390 - transcription export complex 2
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 89 Sc			1 455
+	Sc
		294139 SEM1_YEAST (1-89): 6.2e-39: 126: 100.00		CSN12_YEAST (40-422): 5.39e-86: 271: 16.55
+	Sc
		294127 SEM1_YEAST (1-89): 6.2e-39: 126: 100.00		RPN3_YEAST (200-452): 1.07e-54: 192: 10.98