HitPredict

Interactor 1: TRPM2 (O94759)
Transient receptor potential cation channel subfamily M member 2 (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7) (Transient receptor potential melastatin 2)
Gene: TRPM2

Interactor 2: TRPM2 (O94759)
Transient receptor potential cation channel subfamily M member 2 (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7) (Transient receptor potential melastatin 2)
Gene: TRPM2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.744

The method score is based on:

Property Details
Experiments 31610913, 30467180
Identification Methods affinity chromatography technology, 3D electron microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans, LSDAT_euk~LSDAT_euk
Common GO terms GO:0001659 - temperature homeostasis
GO:0002407 - dendritic cell chemotaxis
GO:0005261 - monoatomic cation channel activity
GO:0005262 - calcium channel activity
GO:0005272 - sodium channel activity
and 31 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1503
Hs

1 1503
+ Dr
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024