HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 306
+	Hs
		294484 RECQ4_HUMAN (1-1208): 0: 794: 100.00		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		294561 RECQ4_HUMAN (1-1208): 0: 794: 100.00		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		294824 RECQ4_HUMAN (1-1208): 0: 794: 100.00		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15
+	Hs
		294308 RECQ4_HUMAN (1-1208): 0: 794: 100.00		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		294794 RECQ4_HUMAN (1-1208): 0: 794: 100.00		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		867573 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45
+	Hs
		134106 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PABP2_HUMAN (96-306): 9.35e-43: 150: 100.00
+	Hs
		789546 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		295510 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		133858 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		134018 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		571369 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		853930 DDX46_HUMAN (244-1038): 7.91e-111: 374: 12.44		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Sp
		140969 DED1_SCHPO (277-841): 2.56e-113: 369: 14.21		PAB2_SCHPO (107-255): 3.12e-34: 124: 48.32
+	Sc
		376580 DED1_YEAST (410-849): 9.08e-110: 359: 16.06		PABP_YEAST (143-260): 3.27e-19: 89.6: 20.17
+	Sc
		624213 DBP1_YEAST (303-876): 1.38e-115: 375: 13.64		PUB1_YEAST (165-255): 5.29e-09: 58.8: 18.48
+	Sc
		624051 DBP2_YEAST (351-848): 1.15e-114: 370: 17.41		PUB1_YEAST (165-255): 5.29e-09: 58.8: 18.48
+	Sc
		415924 DED1_YEAST (410-849): 9.08e-110: 359: 16.06		PUB1_YEAST (165-255): 5.29e-09: 58.8: 18.48