HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: SKAP1 (Q86WV1)
Src kinase-associated phosphoprotein 1 (Src family-associated phosphoprotein 1) (Src kinase-associated phosphoprotein of 55 kDa) (SKAP-55) (pp55)
Gene: SKAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 359
+	Hs
		1050606 WRN_HUMAN (465-856): 8.98e-111: 381: 29.28		SKAP1_HUMAN (1-359): 2.76e-125: 366: 100.00
+	Hs
		867645 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		134083 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PKHA7_HUMAN (57-290): 7.79e-35: 137: 14.02
+	Hs
		133994 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		BTK_HUMAN (105-356): 8.02e-32: 128: 12.72
+	Hs
		801954 RECQ1_HUMAN (446-985): 7.98e-133: 422: 24.39		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		1153317 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		PKHA7_HUMAN (57-290): 7.79e-35: 137: 14.02
+	Hs
		134208 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		181736 DDX3Y_HUMAN (305-843): 2.04e-126: 405: 15.09		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		571491 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		PKHA7_HUMAN (57-290): 7.79e-35: 137: 14.02
+	Mm
		729754 DDX5_MOUSE (374-903): 3.05e-115: 374: 16.18		BTK_MOUSE (105-356): 1.71e-31: 127: 12.37
+	Hs
		1331371 DDX4_HUMAN (178-849): 1.26e-120: 392: 15.95		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		295560 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		1328083 DDX47_HUMAN (439-879): 2.35e-121: 384: 18.32		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		1271662 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		1183360 DDX46_HUMAN (244-1038): 7.91e-111: 374: 12.44		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56
+	Hs
		571596 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		PKHA4_HUMAN (111-267): 1.35e-24: 107: 16.56