HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1208 Hs			1 1121
+	Hs
		294680 RECQ4_HUMAN (1-1208): 0: 794: 100.00		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		294989 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5B_HUMAN (390-646): 2.24e-09: 62.2: 12.78
+	Hs
		294619 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		867636 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		TEP1_HUMAN (64-988): 1.18e-80: 292: 11.42
+	Hs
		867652 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		NLE1_HUMAN (2-141): 9.17e-25: 111: 8.05
+	Hs
		134256 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		FBW1A_HUMAN (30-284): 7.71e-34: 140: 13.41
+	Hs
		134246 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		FBW1B_HUMAN (258-535): 1.92e-29: 126: 13.88
+	Hs
		867626 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		1333547 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		NLE1_HUMAN (2-141): 9.17e-25: 111: 8.05
+	Sc
		715655 SGS1_YEAST (466-853): 2.99e-127: 427: 32.16		CIAO1_YEAST (110-382): 1.5e-14: 78.3: 18.02
+	Hs
		867630 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58
+	Hs
		295566 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		NLE1_HUMAN (2-141): 9.17e-25: 111: 8.05
+	Hs
		134133 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		GEMI5_HUMAN (758-1120): 9.39e-16: 85.1: 9.37
+	Hs
		134154 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		181721 DDX3Y_HUMAN (305-843): 2.04e-126: 405: 15.09		POC1A_HUMAN (727-992): 5.31e-10: 64.8: 12.78
+	Hs
		1288310 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58
+	Hs
		133956 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		295548 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58
+	Hs
		903507 DDX47_HUMAN (439-879): 2.35e-121: 384: 18.32		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		903410 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53