HitPredict

Interactor 1: RECQ4 (O94761)
ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4)
Gene: RECQL4

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29229926
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~DEAD
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 2610
+	Hs
		867664 BLM_HUMAN (474-836): 1.6e-132: 441: 33.42		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1333561 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1328102 DDX47_HUMAN (439-879): 2.35e-121: 384: 18.32		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1271692 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1050634 WRN_HUMAN (465-856): 8.98e-111: 381: 29.28		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		1183374 DDX46_HUMAN (244-1038): 7.91e-111: 374: 12.44		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		571631 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		HECD1_HUMAN (1-2610): 0: 2419: 100.00
+	Hs
		294223 RECQ4_HUMAN (1-1208): 0: 794: 100.00		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		125058 RECQ4_HUMAN (1-1208): 0: 794: 100.00		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		295477 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		1333541 DDX31_HUMAN (197-1041): 1.14e-123: 404: 16.37		SMUF1_HUMAN (2220-2607): 1.5e-116: 391: 19.70
+	Hs
		304227 DDX46_HUMAN (244-1038): 7.91e-111: 374: 12.44		UBR5_HUMAN (1985-2609): 1.07e-116: 418: 16.94
+	Hs
		124993 DDX3X_HUMAN (291-843): 4.68e-127: 407: 14.85		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		571603 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		SMUF1_HUMAN (2220-2607): 1.5e-116: 391: 19.70
+	Hs
		125059 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125704 DDX47_HUMAN (439-879): 2.35e-121: 384: 18.32		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125617 DDX17_HUMAN (306-903): 3.02e-117: 383: 17.50		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		125142 DDX5_HUMAN (374-903): 1.45e-115: 374: 16.18		WWP2_HUMAN (2265-2608): 1.64e-107: 368: 24.86
+	Hs
		295559 RECQ5_HUMAN (463-846): 3.99e-118: 392: 32.45		WWP1_HUMAN (2328-2608): 5.47e-91: 321: 29.27