Interactor 1: FACE1 (O75844)
CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog)
Gene: ZMPSTE24
Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 0.55 | 0.527 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23539603 |
| Identification Methods | x-ray crystallography, protease assay |
| Interaction Type | direct interaction, protein cleavage |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0006998 - nuclear envelope organization |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
