HitPredict

Interactor 1: ST17B (O94768)
Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2)
Gene: STK17B

Interactor 2: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~Pkinase
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 372
+	Hs
		682218 AKT2_HUMAN (1-349): 2.5e-133: 391: 24.02		AKT3_HUMAN (28-371): 1.59e-134: 394: 19.83
+	Hs
		681681 AKT2_HUMAN (1-349): 2.5e-133: 391: 24.02		AKT1_HUMAN (54-371): 5.89e-133: 390: 20.42
+	Hs
		682081 AKT1_HUMAN (1-349): 6.9e-132: 387: 24.51		AKT3_HUMAN (28-371): 1.59e-134: 394: 19.83
+	Mm
		682096 AKT1_MOUSE (1-349): 2.11e-132: 389: 24.51		AKT1_MOUSE (63-371): 2.34e-133: 391: 20.99
+	At
		989461 CDPK1_ARATH (8-358): 8.26e-136: 402: 27.89		KIN10_ARATH (76-364): 5.74e-128: 378: 29.87
+	Hs
		681680 AKT1_HUMAN (1-349): 6.9e-132: 387: 24.51		AKT1_HUMAN (54-371): 5.89e-133: 390: 20.42
+	Mm
		554867 AKT1_MOUSE (1-349): 2.11e-132: 389: 24.51		KPCE_MOUSE (3-371): 6.63e-128: 385: 17.18
+	Hs
		568561 AKT1_HUMAN (1-349): 6.9e-132: 387: 24.51		KAPCA_HUMAN (80-371): 5.89e-131: 380: 20.59
+	At
		1105318 KIN10_ARATH (32-346): 1.08e-131: 388: 27.76		KIN10_ARATH (76-364): 5.74e-128: 378: 29.87
+	At
		187503 KIN10_ARATH (32-346): 1.08e-131: 388: 27.76		CIPKB_ARATH (72-371): 8.51e-129: 378: 25.24
+	Hs
		616676 AKT1_HUMAN (1-349): 6.9e-132: 387: 24.51		KS6B1_HUMAN (73-371): 9.63e-126: 373: 20.51
+	Hs
		682054 AKT1_HUMAN (1-349): 6.9e-132: 387: 24.51		KS6B2_HUMAN (50-371): 1.22e-125: 371: 20.29
+	At
		955190 KIN10_ARATH (32-346): 1.08e-131: 388: 27.76		KIN11_ARATH (90-364): 1.62e-124: 369: 29.58
+	At
		989470 CDPK1_ARATH (8-358): 8.26e-136: 402: 27.89		CIPK1_ARATH (83-345): 5.8e-109: 327: 27.64
+	At
		249832 KIN10_ARATH (32-346): 1.08e-131: 388: 27.76		CIPK6_ARATH (73-371): 1.14e-111: 334: 28.89
+	Mm
		682120 AKT1_MOUSE (1-349): 2.11e-132: 389: 24.51		TRIB3_MOUSE (89-360): 9.59e-93: 283: 54.91
+	Hs
		682202 AKT2_HUMAN (1-349): 2.5e-133: 391: 24.02		TRIB3_HUMAN (89-360): 1.98e-86: 267: 51.65
+	Hs
		681990 AKT1_HUMAN (1-349): 6.9e-132: 387: 24.51		TRIB3_HUMAN (89-360): 1.98e-86: 267: 51.65
+	Dm
		1213376 AKT1_DROME (1-337): 7.99e-131: 389: 25.43		TRIB_DROME (107-338): 2.97e-52: 182: 41.54