HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	33961781, 28179136
Identification Methods	affinity chromatography technology, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0042826 - histone deacetylase binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 668 Hs			1 529
+	Hs
		134816 MTA2_HUMAN (1-668): 0: 776: 100.00		IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38
+	Hs
		295971 MTA2_HUMAN (1-668): 0: 776: 100.00		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	Hs
		134890 MTA1_HUMAN (1-668): 0: 704: 56.24		IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38
+	Hs
		131430 MTA1_HUMAN (1-668): 0: 704: 56.24		IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06
+	Hs
		853588 MTA1_HUMAN (1-668): 0: 704: 56.24		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	Hs
		168665 MTA3_HUMAN (1-570): 0: 660: 64.24		IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02
+	Hs
		853695 MTA3_HUMAN (1-570): 0: 660: 64.24		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	Hs
		91456 E7EQY4_HUMAN (1-500): 0: 614: 69.38		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	Hs
		131502 Q9BRL8_HUMAN (448-668): 6.32e-57: 195: 34.23		IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06