HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: IKZF1 (Q13422)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 35583604
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization GO:0032991 - protein-containing complex GO:0045892 - negative regulation of DNA-templated transcription and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 668 Hs			1 519
+	Hs
		1031846 MTA1_HUMAN (1-668): 0: 704: 56.24		IKZF1_HUMAN (1-519): 0: 664: 100.00
+	Hs
		1033722 MTA3_HUMAN (1-570): 0: 660: 64.24		IKZF1_HUMAN (1-519): 0: 664: 100.00
+	Hs
		296171 MTA2_HUMAN (1-668): 0: 776: 100.00		IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82
+	Hs
		1031971 MTA1_HUMAN (1-668): 0: 704: 56.24		IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82
+	Hs
		1350409 RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62		IKZF3_HUMAN (11-515): 4.42e-139: 413: 53.82