HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: MB3L1 (Q8WWY6)
Methyl-CpG-binding domain protein 3-like 1 (MBD3-like protein 1)
Gene: MBD3L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 15456747, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 668 Hs			1 194
+	Hs
		295905 MTA2_HUMAN (1-668): 0: 776: 100.00		MBD3_HUMAN (1-193): 3.4e-102: 297: 44.56
+	Mm
		1351672 MTA2_MOUSE (1-668): 0: 776: 98.50		MBD3_MOUSE (1-193): 1.26e-101: 296: 43.52
+	Hs
		296160 MTA2_HUMAN (1-668): 0: 776: 100.00		MBD2_HUMAN (1-182): 5.61e-85: 258: 41.76
+	Mm
		1351673 MTA2_MOUSE (1-668): 0: 776: 98.50		MBD2_MOUSE (1-182): 1.15e-84: 257: 41.76
+	Hs
		328546 MTA1_HUMAN (1-668): 0: 704: 56.24		MBD3_HUMAN (1-193): 3.4e-102: 297: 44.56
+	Mm
		1225274 MTA1_MOUSE (1-668): 0: 696: 56.24		MBD3_MOUSE (1-193): 1.26e-101: 296: 43.52
+	Hs
		1031914 MTA1_HUMAN (1-668): 0: 704: 56.24		MB3L1_HUMAN (1-194): 1.26e-98: 285: 100.00
+	Hs
		296082 MTA2_HUMAN (1-668): 0: 776: 100.00		MB3L2_HUMAN (26-187): 5.81e-61: 190: 45.73
+	Hs
		1031965 MTA1_HUMAN (1-668): 0: 704: 56.24		MBD2_HUMAN (1-182): 5.61e-85: 258: 41.76
+	Hs
		328646 MTA3_HUMAN (1-570): 0: 660: 64.24		MBD3_HUMAN (1-193): 3.4e-102: 297: 44.56
+	Hs
		1263076 MTA3_HUMAN (1-570): 0: 660: 64.24		MB3L1_HUMAN (1-194): 1.26e-98: 285: 100.00
+	Hs
		1312035 MTA3_HUMAN (1-570): 0: 660: 64.24		MBD2_HUMAN (1-182): 5.61e-85: 258: 41.76
+	Hs
		1031910 MTA1_HUMAN (1-668): 0: 704: 56.24		MB3L2_HUMAN (26-187): 5.81e-61: 190: 45.73
+	Hs
		1246264 MTA3_HUMAN (1-570): 0: 660: 64.24		MB3L2_HUMAN (26-187): 5.81e-61: 190: 45.73
+	Dm
		81426 B7Z0T5_DROME (10-662): 0: 596: 40.19		Q9VHB7_DROME (19-172): 3.67e-59: 190: 28.66