HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: LMBL2 (Q969R5)
Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2)
Gene: L3MBTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 668 Hs			1 705
+	Mm
		886513 MTA2_MOUSE (1-668): 0: 776: 98.50		LMBL2_MOUSE (1-705): 0: 1001: 90.92
+	Hs
		1031921 MTA1_HUMAN (1-668): 0: 704: 56.24		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Mm
		886507 MTA3_MOUSE (1-573): 0: 643: 64.02		LMBL2_MOUSE (1-705): 0: 1001: 90.92
+	Hs
		1282168 RERE_HUMAN (5-664): 8.13e-140: 447: 20.70		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		1282176 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		1231961 MIER2_HUMAN (115-377): 8e-53: 192: 21.20		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		1350406 RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62		SMBT1_HUMAN (160-638): 0: 556: 32.19
+	Mm
		1207992 RCOR2_MOUSE (134-664): 3.46e-82: 271: 16.05		SMBT1_MOUSE (159-638): 0: 546: 31.44
+	Hs
		1355483 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		SMBT1_HUMAN (160-638): 0: 556: 32.19
+	Mm
		1206855 RCOR2_MOUSE (134-664): 3.46e-82: 271: 16.05		LMBL3_MOUSE (140-481): 2.62e-59: 216: 24.00
+	Hs
		1295445 RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62		LMBL3_HUMAN (140-285): 2.23e-26: 117: 26.03
+	Dm
		1123845 RCOR_DROME (146-330): 2.58e-25: 113: 28.42		SCM_DROME (397-697): 1.12e-74: 260: 26.06
+	Hs
		1295450 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		LMBL3_HUMAN (140-285): 2.23e-26: 117: 26.03
+	Dm
		1123843 RCOR_DROME (146-330): 2.58e-25: 113: 28.42		Q9VB52_DROME (148-294): 5.52e-17: 87.9: 22.45