HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: BC11A (Q9H165)
B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)
Gene: BCL11A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	24981860, 16091750, 26816381
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 668 Hs			1 835
+	Hs
		1031945 MTA1_HUMAN (1-668): 0: 704: 56.24		BC11A_HUMAN (1-835): 0: 718: 100.00
+	Hs
		1312020 MTA3_HUMAN (1-570): 0: 660: 64.24		BC11A_HUMAN (1-835): 0: 718: 100.00
+	Hs
		296128 MTA2_HUMAN (1-668): 0: 776: 100.00		BC11B_HUMAN (1-835): 0: 596: 57.77
+	Hs
		1031943 MTA1_HUMAN (1-668): 0: 704: 56.24		BC11B_HUMAN (1-835): 0: 596: 57.77
+	Hs
		1312018 MTA3_HUMAN (1-570): 0: 660: 64.24		BC11B_HUMAN (1-835): 0: 596: 57.77
+	Hs
		1260513 MTA3_HUMAN (1-570): 0: 660: 64.24		ZN296_HUMAN (375-451): 3.26e-11: 68.6: 46.84
+	Hs
		1312858 RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62		ZSA5A_HUMAN (369-427): 1.8e-18: 91.7: 42.37
+	Hs
		1223941 RCOR2_HUMAN (134-666): 1.84e-82: 271: 16.25		ZSA5A_HUMAN (369-427): 1.8e-18: 91.7: 42.37
+	Hs
		1312860 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		ZSA5A_HUMAN (369-427): 1.8e-18: 91.7: 42.37