HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: SALL4 (Q9UJQ4)
Sal-like protein 4 (Zinc finger protein 797) (Zinc finger protein SALL4)
Gene: SALL4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 668 Hs			1 1053
+	Mm
		1207435 MTA2_MOUSE (1-668): 0: 776: 98.50		SALL4_MOUSE (1-1053): 0: 718: 72.51
+	Mm
		1207419 MTA1_MOUSE (1-668): 0: 696: 56.24		SALL4_MOUSE (1-1053): 0: 718: 72.51
+	Mm
		1207425 MTA3_MOUSE (1-573): 0: 643: 64.02		SALL4_MOUSE (1-1053): 0: 718: 72.51
+	Hs
		1031970 MTA1_HUMAN (1-668): 0: 704: 56.24		SALL4_HUMAN (1-1053): 0: 600: 100.00
+	Hs
		1312041 MTA3_HUMAN (1-570): 0: 660: 64.24		SALL4_HUMAN (1-1053): 0: 600: 100.00
+	Hs
		296152 MTA2_HUMAN (1-668): 0: 776: 100.00		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83
+	Hs
		1031957 MTA1_HUMAN (1-668): 0: 704: 56.24		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83
+	Hs
		1312027 MTA3_HUMAN (1-570): 0: 660: 64.24		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83
+	Ce
		107516 EGL27_CAEEL (3-557): 3.83e-125: 400: 19.37		SEM4_CAEEL (872-920): 2.28e-09: 63.5: 63.27
+	Hs
		1356503 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		SALL2_HUMAN (682-920): 7.17e-17: 88.4: 22.41
+	Hs
		1345501 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		SALL1_HUMAN (624-678): 2.98e-09: 63.3: 29.83