HitPredict

Interactor 1: MTA2 (O94776)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
Gene: MTA2

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	26496610, 31753913, 25593309
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 668 Hs			1 1186
+	Hs
		1031972 MTA1_HUMAN (1-668): 0: 704: 56.24		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		1312043 MTA3_HUMAN (1-570): 0: 660: 64.24		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		91460 E7EQY4_HUMAN (1-500): 0: 614: 69.38		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		1350536 RERE_HUMAN (5-664): 8.13e-140: 447: 20.70		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		1350411 RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		1223947 RCOR2_HUMAN (134-666): 1.84e-82: 271: 16.25		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		1356487 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		296001 MTA2_HUMAN (1-668): 0: 776: 100.00		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		1017290 MTA1_HUMAN (1-668): 0: 704: 56.24		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		1017343 MTA3_HUMAN (1-570): 0: 660: 64.24		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		1262830 RERE_HUMAN (5-664): 8.13e-140: 447: 20.70		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		203472 RERE_HUMAN (5-664): 8.13e-140: 447: 20.70		MTG8R_HUMAN (949-1120): 2.94e-44: 172: 20.46
+	Hs
		600249 RERE_HUMAN (5-664): 8.13e-140: 447: 20.70		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		1262828 RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		170419 RCOR2_HUMAN (134-666): 1.84e-82: 271: 16.25		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		254013 RCOR3_HUMAN (147-666): 2.93e-89: 288: 14.62		MTG16_HUMAN (948-1103): 2.32e-42: 167: 24.85
+	Hs
		164501 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		TRI66_HUMAN (20-302): 1.21e-49: 194: 19.60
+	Hs
		1262836 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		600187 RCOR2_HUMAN (134-666): 1.84e-82: 271: 16.25		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57
+	Hs
		600251 RCOR1_HUMAN (145-597): 1.42e-65: 225: 15.27		TAF1_HUMAN (14-254): 1.28e-24: 114: 20.57