HitPredict

Interactor 1: UBP1 (O94782)
Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment]
Gene: USP1

Interactor 2: PHLP2 (Q6ZVD8)
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)
Gene: PHLPP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	27463890, 27880917, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 785 Hs			1 1323
+	Hs
		232750 UBP1_HUMAN (1-785): 1.25e-180: 538: 100.00		PHLP1_HUMAN (36-1300): 0: 845: 53.04
+	Mm
		1206741 UBP1_MOUSE (1-785): 3.61e-173: 519: 88.17		PHLP1_MOUSE (37-1300): 0: 845: 52.89
+	Hs
		905387 UBP46_HUMAN (65-298): 1.53e-41: 157: 20.00		PHLP2_HUMAN (1-1323): 0: 993: 100.00
+	Hs
		259292 UBP12_HUMAN (64-306): 1.57e-39: 152: 20.54		PHLP2_HUMAN (1-1323): 0: 993: 100.00
+	Hs
		233026 UBP15_HUMAN (361-655): 6.89e-46: 179: 16.77		PHLP1_HUMAN (36-1300): 0: 845: 53.04
+	Hs
		232831 UBP46_HUMAN (65-298): 1.53e-41: 157: 20.00		PHLP1_HUMAN (36-1300): 0: 845: 53.04
+	Hs
		232744 UBP12_HUMAN (64-306): 1.57e-39: 152: 20.54		PHLP1_HUMAN (36-1300): 0: 845: 53.04
+	Hs
		905408 UBP46_HUMAN (65-298): 1.53e-41: 157: 20.00		SHOC2_HUMAN (251-624): 1.1e-23: 109: 26.84
+	Hs
		1273970 UBP7_HUMAN (57-351): 1.5e-15: 83.3: 13.22		SHOC2_HUMAN (251-624): 1.1e-23: 109: 26.84