HitPredict

Interactor 1: UBP1 (O94782)
Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.4.19.12) (Deubiquitinating enzyme 1) (hUBP) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) [Cleaved into: Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment]
Gene: USP1

Interactor 2: WDR48 (Q8TAF3)
WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80)
Gene: WDR48

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.992

The method score is based on:

Property Details
Experiments 18082604, 24850727, 27463890, 27239033, 30456385, 30335599, 31796584, 19615732, 19075014, 25744535, 26388029, 28514442, 27986371, 32951278, 23463011, 24981860, 33961781, 33795880, 34128540, 34154657 and 5 others

more...
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, biochemical, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~WD40
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0046427 - positive regulation of receptor signaling pathway via JAK-STAT
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 785
Hs

1 677
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024