HitPredict

Interactor 1: TPPP (O94811)
Tubulin polymerization-promoting protein (TPPP) (EC 3.6.5.-) (25 kDa brain-specific protein) (TPPP/p25) (p24) (p25-alpha)
Gene: TPPP

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.55	0.617

The method score is based on:

Property	Details
Experiments	27671864, 20849899
Identification Methods	pull down, affinity chromatography technology, nuclear magnetic resonance, circular dichroism, enzyme linked immunosorbent assay, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000287 - magnesium ion binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol and 1 others more... GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024