Interactor 1: SLIT2 (O94813)
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]
Gene: SLIT2

Interactor 2: SLIT2 (O94813)
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]
Gene: SLIT2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 19498462
Identification Methods x-ray crystallography, dynamic light scattering
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, Laminin_G_1~Laminin_G_1, LRR_1~LRR_1, LRR_1~LRR_8, LRR_8~LRR_8, LRR_8~LRRCT, LRR_8~LRRNT, LRRNT~LRRNT
Common GO terms GO:0001657 - ureteric bud development
GO:0001933 - negative regulation of protein phosphorylation
GO:0002042 - cell migration involved in sprouting angiogenesis
GO:0002689 - negative regulation of leukocyte chemotaxis
GO:0003180 - aortic valve morphogenesis
and 45 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1529
Hs

1 1529
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024