Interactor 1: ATG12 (O94817)
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)
Gene: ATG12

Interactor 2: ATG7 (O95352)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (hAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 28253953, 20562859, 11096062
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0005829 - cytosol
GO:0016236 - macroautophagy
GO:0034727 - piecemeal microautophagy of the nucleus
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 140
Hs

1 703
+ Mm
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024