Interactor 1: ATG12 (O94817)
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)
Gene: ATG12

Interactor 2: ATG5 (Q9H1Y0)
Autophagy protein 5 (APG5-like) (Apoptosis-specific protein)
Gene: ATG5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.975

The method score is based on:

Property Details
Experiments 17353931, 32129924, 35271311, 20562859, 28253979, 33024031, 33961781, 31612776, 22342342, 12207896
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, covalent binding, association

The annotation score is based on:

Property Details
Interacting Pfam domains APG12~APG5
Common GO terms GO:0000045 - autophagosome assembly
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0016236 - macroautophagy
GO:0030670 - phagocytic vesicle membrane
and 10 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 140
Hs

1 275
+ Mm
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024