HitPredict

Interactor 1: DGAT1 (O75907)
Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (ACAT-related gene product 1) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)
Gene: DGAT1

Interactor 2: DGAT1 (O75907)
Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (ACAT-related gene product 1) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)
Gene: DGAT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 11672446, 32433610, 32433611
Identification Methods affinity chromatography technology, pull down, 3D electron microscopy, molecular sieving
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MBOAT~MBOAT
Common GO terms GO:0003846 - 2-acylglycerol O-acyltransferase activity
GO:0004144 - diacylglycerol O-acyltransferase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006640 - monoacylglycerol biosynthetic process
and 11 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 488
Hs

1 488
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025