HitPredict

Interactor 1: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Interactor 2: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20516061
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HMG_box~HMG_box
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0031490 - chromatin DNA binding GO:0072357 - PTW/PP1 phosphatase complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 621
+	Hs
		297540 TOX4_HUMAN (1-621): 4.57e-110: 345: 100.00		TOX2_HUMAN (6-416): 5.99e-45: 168: 28.64
+	Hs
		297488 TOX4_HUMAN (1-621): 4.57e-110: 345: 100.00		SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11
+	Hs
		299609 TOX2_HUMAN (6-416): 5.99e-45: 168: 28.64		TOX_HUMAN (6-435): 4.26e-44: 166: 36.67
+	Hs
		869804 PMS1_HUMAN (7-446): 1.28e-42: 166: 13.05		PMS1_HUMAN (7-446): 1.28e-42: 166: 13.05
+	Hs
		1355192 HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41		HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41
+	Dm
		1212946 PANG2_DROME (90-452): 2.84e-34: 141: 11.81		PANG2_DROME (90-452): 2.84e-34: 141: 11.81
+	Dm
		954936 PANG1_DROME (31-452): 2.12e-34: 141: 12.76		PANG1_DROME (31-452): 2.12e-34: 141: 12.76
+	Hs
		996946 HMGX4_HUMAN (55-335): 2.61e-40: 157: 20.41		SSRP1_HUMAN (148-386): 3.7e-29: 124: 18.11
+	Hs
		727930 SOX6_HUMAN (31-416): 2.07e-34: 141: 13.03		HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56
+	Hs
		1342331 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56
+	Hs
		727933 SOX6_HUMAN (31-416): 2.07e-34: 141: 13.03		HM20B_HUMAN (186-447): 4.94e-34: 133: 18.56
+	Mm
		653452 LEF1_MOUSE (29-321): 3.92e-39: 150: 12.17		HMGB2_MOUSE (139-314): 2.33e-31: 123: 18.38
+	Hs
		1342340 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		HM20B_HUMAN (186-447): 4.94e-34: 133: 18.56
+	Dm
		1212959 PANG2_DROME (90-452): 2.84e-34: 141: 11.81		Q9VUD3_DROME (216-333): 3.05e-30: 127: 21.67
+	Dm
		114457 PANG1_DROME (31-452): 2.12e-34: 141: 12.76		M9PCG2_DROME (216-333): 1.35e-29: 125: 21.67
+	Hs
		727836 SOX6_HUMAN (31-416): 2.07e-34: 141: 13.03		SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61
+	Hs
		818487 HM20A_HUMAN (133-423): 7.93e-36: 139: 16.56		SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61