HitPredict

Interactor 1: TOX4 (O94842)
TOX high mobility group box family member 4 (Epidermal Langerhans cell protein LCP1)
Gene: TOX4

Interactor 2: SPB8 (P50452)
Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8)
Gene: SERPINB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 374
+	Hs
		817802 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		SPB8_HUMAN (1-374): 7.43e-168: 475: 100.00
+	Hs
		397016 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		PAI2_HUMAN (1-374): 4.69e-159: 454: 42.79
+	Hs
		675627 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		ILEU_HUMAN (1-374): 1.27e-159: 454: 51.72
+	Hs
		818577 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		SPB13_HUMAN (1-374): 2.59e-155: 443: 39.03
+	Hs
		818366 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		SPB12_HUMAN (1-374): 8.9e-145: 417: 39.51
+	Hs
		271857 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		SPB7_HUMAN (1-374): 1.65e-144: 416: 36.36
+	Hs
		344108 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		ANT3_HUMAN (3-374): 1.73e-143: 416: 37.34
+	Hs
		738732 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		SPB5_HUMAN (1-374): 8.53e-141: 406: 37.73
+	Hs
		344176 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		A1AT_HUMAN (2-374): 1.43e-139: 404: 31.75
+	Hs
		297520 TOX4_HUMAN (1-621): 4.57e-110: 345: 100.00		SPA12_HUMAN (3-374): 4.99e-52: 180: 29.71
+	Hs
		397097 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		PAI1_HUMAN (4-374): 1.29e-133: 389: 30.50
+	Hs
		818224 SOX2_HUMAN (185-480): 3.81e-31: 125: 13.61		SPA12_HUMAN (3-374): 4.99e-52: 180: 29.71