HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: BRE1A (Q5VTR2)
E3 ubiquitin-protein ligase BRE1A (BRE1-A) (hBRE1) (EC 2.3.2.27) (RING finger protein 20) (RING-type E3 ubiquitin transferase BRE1A)
Gene: RNF20

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 696 Hs			1 975
+	Hs
		256190 RHBT1_HUMAN (1-696): 0: 541: 100.00		BRE1B_HUMAN (1-974): 4.61e-62: 230: 56.49
+	Hs
		254424 RHBT1_HUMAN (1-696): 0: 541: 100.00		ROCK2_HUMAN (96-897): 2.15e-15: 83.5: 14.08
+	Hs
		213997 SPOP_HUMAN (300-648): 8.45e-74: 244: 15.32		BRE1B_HUMAN (1-974): 4.61e-62: 230: 56.49
+	Hs
		724757 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		MYH9_HUMAN (235-957): 1.06e-32: 139: 11.26
+	Mm
		823529 CDC42_MOUSE (12-218): 1.55e-89: 279: 37.14		CTRO_MOUSE (49-906): 9.26e-18: 91.2: 15.30
+	Sc
		350851 YPT1_YEAST (8-238): 1.29e-70: 230: 19.23		USO1_YEAST (39-860): 3.87e-28: 125: 13.11
+	Hs
		725125 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		MYH10_HUMAN (604-944): 1.39e-12: 74.4: 10.85
+	Hs
		551652 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		DESP_HUMAN (225-919): 9.01e-12: 71.9: 16.12
+	Hs
		254445 RHOQ_HUMAN (10-213): 9.06e-84: 264: 37.68		ROCK2_HUMAN (96-897): 2.15e-15: 83.5: 14.08
+	Hs
		894274 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		MY18A_HUMAN (326-919): 1.43e-10: 67.7: 15.69
+	Hs
		564633 RHOQ_HUMAN (10-213): 9.06e-84: 264: 37.68		MY18A_HUMAN (326-919): 1.43e-10: 67.7: 15.69
+	Mm
		823530 RAC1_MOUSE (12-219): 7.28e-73: 235: 35.55		CTRO_MOUSE (49-906): 9.26e-18: 91.2: 15.30
+	Hs
		254468 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		ROCK2_HUMAN (96-897): 2.15e-15: 83.5: 14.08
+	Hs
		148653 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		CTRO_HUMAN (49-890): 9.97e-15: 81.5: 14.94
+	Hs
		254466 RB11A_HUMAN (5-250): 9.13e-72: 233: 17.67		ROCK2_HUMAN (96-897): 2.15e-15: 83.5: 14.08
+	Hs
		148636 RAB1A_HUMAN (1-239): 4.59e-72: 234: 16.94		CTRO_HUMAN (49-890): 9.97e-15: 81.5: 14.94
+	Hs
		254462 RAC3_HUMAN (12-208): 1.21e-70: 230: 39.50		ROCK2_HUMAN (96-897): 2.15e-15: 83.5: 14.08
+	Hs
		925488 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		MY18A_HUMAN (326-919): 1.43e-10: 67.7: 15.69
+	Hs
		545537 RAC2_HUMAN (12-219): 3.63e-71: 231: 36.97		MY18A_HUMAN (326-919): 1.43e-10: 67.7: 15.69
+	Hs
		892521 RAC3_HUMAN (12-208): 1.21e-70: 230: 39.50		MY18A_HUMAN (326-919): 1.43e-10: 67.7: 15.69