HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005882 - intermediate filament
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 3515 Hs			1 382
+	Hs
		567012 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		566963 UTRN_HUMAN (1888-3408): 5.82e-46: 186: 10.65		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		567050 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Rn
		435402 Q6XDA1_RAT (1329-2324): 1.56e-28: 129: 12.24		CXA1_RAT (1-382): 0: 546: 97.64
+	Hs
		567061 GOGB1_HUMAN (2376-3513): 6.18e-27: 124: 7.95		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		567331 MACF1_HUMAN (2457-3438): 8.06e-18: 94.1: 10.20		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		567199 SYNE2_HUMAN (2423-3089): 7.82e-11: 70.9: 18.90		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		164637 SPTN2_HUMAN (1494-3500): 1.84e-87: 323: 14.53		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39
+	Hs
		567019 DYST_HUMAN (1791-2787): 2.94e-09: 65.9: 9.30		CXA1_HUMAN (1-382): 0: 545: 100.00
+	Hs
		963365 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39
+	Hs
		1045454 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39
+	Hs
		1059239 GOGB1_HUMAN (2376-3513): 6.18e-27: 124: 7.95		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39
+	Hs
		1230284 SYNE1_HUMAN (2469-3191): 6.71e-12: 74.7: 13.10		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39
+	Hs
		1230304 SYNE2_HUMAN (2423-3089): 7.82e-11: 70.9: 18.90		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39
+	Hs
		974109 DYST_HUMAN (1791-2787): 2.94e-09: 65.9: 9.30		CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39