HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3515 Hs			1 245
+	Hs
		297821 K0754_HUMAN (1-3515): 0: 1797: 100.00		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		297815 K0754_HUMAN (1-3515): 0: 1797: 100.00		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Hs
		506805 SPTB1_HUMAN (1491-3124): 3.29e-104: 377: 15.78		1433T_HUMAN (1-245): 2.6e-140: 395: 79.59
+	Mm
		926814 Q68FG2_MOUSE (1494-3515): 8.18e-99: 360: 14.99		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Mm
		434798 SPTA1_MOUSE (1319-3438): 1.36e-88: 327: 13.48		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Mm
		926806 SPTB2_MOUSE (1422-2955): 4.85e-71: 269: 16.42		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Hs
		926931 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		551660 DESP_HUMAN (1724-3478): 3.52e-47: 191: 8.99		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		904449 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		963298 SPTB2_HUMAN (1433-2955): 2.11e-69: 263: 16.60		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Mm
		82753 B9EKJ1_MOUSE (2534-3437): 2.69e-34: 148: 14.16		1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59
+	Hs
		927025 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		909544 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		1433E_HUMAN (2-241): 9.9e-144: 403: 68.18
+	Hs
		683333 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		1433B_HUMAN (1-242): 9.01e-140: 393: 87.60
+	Mm
		82777 B9EKJ1_MOUSE (2534-3437): 2.69e-34: 148: 14.16		1433B_MOUSE (1-242): 3.77e-128: 364: 87.19
+	Hs
		551656 DESP_HUMAN (1724-3478): 3.52e-47: 191: 8.99		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		551677 DESP_HUMAN (1724-3478): 3.52e-47: 191: 8.99		1433F_HUMAN (2-240): 1.26e-107: 312: 74.49
+	Hs
		809095 UTRN_HUMAN (1888-3408): 5.82e-46: 186: 10.65		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		904543 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		1433G_HUMAN (1-240): 2.37e-108: 314: 74.59
+	Hs
		684024 SPTN1_HUMAN (2534-3437): 5.67e-34: 147: 13.94		1433S_HUMAN (1-237): 8.27e-104: 302: 71.97