Interactor 1: UFL1 (O94874)
E3 UFM1-protein ligase 1 (EC 2.3.2.-) (E3 UFM1-protein transferase 1) (Multiple alpha-helix protein located at ER) (Novel LZAP-binding protein) (Regulator of C53/LZAP and DDRGK1)
Gene: UFL1

Interactor 2: UFC1 (Q9Y3C8)
Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1)
Gene: UFC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.55 0.675

The method score is based on:

Property Details
Experiments 32545848, 32807901, 33961781, 37595036
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, isothermal titration calorimetry
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0034976 - response to endoplasmic reticulum stress
GO:0061709 - reticulophagy
GO:0071568 - UFM1 transferase activity
GO:0071569 - protein ufmylation
and 1 others

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Homologous interactions 0

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Last updated: 15 Jul 2024