HitPredict

Interactor 1: SRBS2 (O94875)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)
Gene: SORBS2

Interactor 2: VINC (P18206)
Vinculin (Metavinculin) (MV)
Gene: VCL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10521485
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1100 Hs			1 1134
+	Mm
		1113246 SRBS2_MOUSE (1-1100): 0: 711: 86.74		VINC_MOUSE (1-1134): 0: 811: 90.65
+	Hs
		575737 SPTN1_HUMAN (86-954): 3.53e-63: 238: 11.98		VINC_HUMAN (1-1134): 0: 893: 100.00
+	Hs
		282306 NEBL_HUMAN (415-1100): 5.65e-48: 188: 12.32		VINC_HUMAN (1-1134): 0: 893: 100.00
+	Hs
		235472 VINEX_HUMAN (536-1100): 1.68e-35: 146: 25.65		VINC_HUMAN (1-1134): 0: 893: 100.00
+	Hs
		298955 SRBS2_HUMAN (1-1100): 0: 744: 100.00		CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48
+	Hs
		575836 SRBS1_HUMAN (713-921): 7.81e-12: 72: 16.90		VINC_HUMAN (1-1134): 0: 893: 100.00
+	Ce
		104695 SRBS1_CAEEL (711-1023): 4.14e-26: 118: 23.17		VINC_CAEEL (1-1132): 0: 674: 26.08
+	Dm
		220701 Q86P80_DROME (563-1099): 5.15e-44: 172: 23.96		VINC_DROME (1-933): 5.44e-126: 411: 28.23
+	Dm
		2230 A0A0B4K6W0_DROME (632-1099): 1.07e-27: 124: 26.41		VINC_DROME (1-933): 5.44e-126: 411: 28.23
+	Dm
		52981 A1Z866_DROME (557-1100): 1.54e-11: 70.4: 13.87		VINC_DROME (1-933): 5.44e-126: 411: 28.23
+	Hs
		282311 NEBL_HUMAN (415-1100): 5.65e-48: 188: 12.32		CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48
+	Hs
		716762 SRBS1_HUMAN (713-921): 7.81e-12: 72: 16.90		CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48