HitPredict

Interactor 1: SRBS2 (O94875)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)
Gene: SORBS2

Interactor 2: CAZA2 (P47755)
F-actin-capping protein subunit alpha-2 (CapZ alpha-2)
Gene: CAPZA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1100 Hs			1 286
+	Hs
		813018 SPTN1_HUMAN (86-954): 3.53e-63: 238: 11.98		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00
+	Hs
		857099 GRB2_HUMAN (743-923): 8.99e-28: 114: 17.90		CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71
+	Hs
		813005 MYO1E_HUMAN (874-1100): 1.36e-21: 103: 16.00		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00
+	Hs
		813025 SRC8_HUMAN (918-1099): 3.51e-17: 88.5: 14.84		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00
+	Hs
		857125 SRC8_HUMAN (918-1099): 3.51e-17: 88.5: 14.84		CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71
+	Hs
		813121 SH3K1_HUMAN (942-1100): 2.45e-12: 73.2: 30.86		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00
+	Hs
		813227 CD2AP_HUMAN (944-1100): 5.5e-12: 72: 29.70		CAZA2_HUMAN (1-286): 2.44e-159: 446: 100.00
+	Hs
		857188 SH3K1_HUMAN (942-1100): 2.45e-12: 73.2: 30.86		CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71
+	Hs
		857263 CD2AP_HUMAN (944-1100): 5.5e-12: 72: 29.70		CAZA1_HUMAN (1-286): 5.83e-156: 438: 86.71