HitPredict

Interactor 1: SRBS2 (O94875)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)
Gene: SORBS2

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	25416956, 16189514, 36931259
Identification Methods	two hybrid, affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005925 - focal adhesion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1100 Hs			1 255
+	Hs
		299007 SRBS2_HUMAN (1-1100): 0: 744: 100.00		V9HW98_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Mm
		910242 SRBS2_MOUSE (1-1100): 0: 711: 86.74		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		909544 SPTN1_HUMAN (86-954): 3.53e-63: 238: 11.98		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909427 GRB2_HUMAN (743-923): 8.99e-28: 114: 17.90		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909634 SH319_HUMAN (852-921): 3.89e-13: 75.9: 37.50		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909744 SH3R1_HUMAN (981-1098): 4.65e-12: 72.6: 30.33		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909979 SRBS1_HUMAN (713-921): 7.81e-12: 72: 16.90		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909849 SH3R3_HUMAN (1011-1098): 1.94e-10: 67.2: 28.26		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Sp
		788710 CDC15_SCHPO (519-1100): 1.89e-14: 80.5: 14.61		RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77