HitPredict

Interactor 1: FARP2 (O94887)
FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)
Gene: FARP2

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras, PH~Ras, Ras~RhoGEF
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1054 Hs			1 189
+	Hs
		299226 FARP2_HUMAN (1-1054): 0: 847: 100.00		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		350721 FARP1_HUMAN (1-1039): 0: 737: 52.90		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1070476 FARP1_HUMAN (1-1039): 0: 737: 52.90		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		349026 FARP1_HUMAN (1-1039): 0: 737: 52.90		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		350075 FGD1_HUMAN (363-1037): 9.47e-125: 406: 22.15		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		350574 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1070407 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		349830 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		505600 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02
+	Hs
		505636 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		348937 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		348485 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		348923 E41L1_HUMAN (4-539): 4.5e-116: 381: 27.89		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349662 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		349088 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		914374 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		505614 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		895282 E41L5_HUMAN (7-632): 2.56e-119: 385: 22.74		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		505601 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		505642 EPB41_HUMAN (3-548): 2.87e-117: 383: 28.10		RB11B_HUMAN (4-184): 2.97e-73: 221: 32.79