Interactor 1: FARP2 (O94887)
FERM, ARHGEF and pleckstrin domain-containing protein 2 (FERM domain-including RhoGEF) (FIR) (FERM, RhoGEF and pleckstrin domain-containing protein 2) (Pleckstrin homology domain-containing family C member 3) (PH domain-containing family C member 3)
Gene: FARP2

Interactor 2: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 32203420, unassigned2213
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~PH, CAMSAP_CH~PH, PH~PH, PH~RhoGEF, PH~SH3_1, C1_1~RhoGEF, RhoGEF~RhoGEF, RhoGEF~SH3_1
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1054
Hs

1 845
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce

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Last updated: 15 Jul 2024