HitPredict

Interactor 1: LRIG2 (O94898)
Leucine-rich repeats and immunoglobulin-like domains protein 2 (LIG-2)
Gene: LRIG2

Interactor 2: SPSB4 (Q96A44)
SPRY domain-containing SOCS box protein 4 (SSB-4)
Gene: SPSB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1065 Hs			1 273
+	Hs
		299581 LRIG2_HUMAN (2-697): 1.93e-94: 326: 18.22		SPSB2_HUMAN (1-273): 8.89e-98: 289: 50.92
+	Hs
		1283442 LRIG1_HUMAN (2-187): 1.1e-24: 113: 14.49		SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00
+	Hs
		1166660 LRIG3_HUMAN (3-187): 3.61e-19: 96: 12.04		SPSB4_HUMAN (1-273): 1.22e-129: 370: 100.00
+	Hs
		770224 GPV_HUMAN (28-548): 4.05e-83: 282: 24.72		RN123_HUMAN (87-239): 2.19e-33: 130: 21.38
+	Hs
		1294952 LRIG1_HUMAN (2-187): 1.1e-24: 113: 14.49		SPSB2_HUMAN (1-273): 8.89e-98: 289: 50.92
+	Hs
		1166663 LRIG3_HUMAN (3-187): 3.61e-19: 96: 12.04		SPSB2_HUMAN (1-273): 8.89e-98: 289: 50.92
+	Hs
		1172496 ROBO1_HUMAN (694-1059): 8.45e-56: 214: 11.99		TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37
+	Hs
		1171804 ROBO2_HUMAN (694-1061): 7.39e-52: 201: 11.23		TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37
+	Hs
		1171255 LRIG1_HUMAN (2-187): 1.1e-24: 113: 14.49		TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37
+	Hs
		1171906 LRC4B_HUMAN (360-785): 5.38e-23: 107: 17.93		TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37
+	Hs
		1171055 PXDN_HUMAN (2-99): 8.52e-13: 75.2: 10.20		TRI67_HUMAN (52-232): 1.14e-36: 139: 19.37
+	Hs
		1140562 LRR70_HUMAN (99-345): 4e-12: 72.4: 27.89		RN123_HUMAN (87-239): 2.19e-33: 130: 21.38