HitPredict

Interactor 1: TOX (O94900)
Thymocyte selection-associated high mobility group box protein TOX (Thymus high mobility group box protein TOX)
Gene: TOX

Interactor 2: FOXP4 (Q8IVH2)
Forkhead box protein P4 (Fork head-related protein-like A)
Gene: FOXP4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29365100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 526 Hs			1 680
+	Hs
		299610 TOX_HUMAN (1-526): 2.01e-94: 298: 100.00		FOXP1_HUMAN (1-679): 1.33e-169: 503: 54.38
+	Hs
		727774 SOX5_HUMAN (7-363): 8.3e-45: 170: 13.02		FOXP4_HUMAN (1-669): 0: 599: 100.00
+	Hs
		727892 SOX6_HUMAN (17-425): 1.1e-37: 149: 11.62		FOXP4_HUMAN (1-669): 0: 599: 100.00
+	Hs
		1217570 SOX13_HUMAN (70-398): 1.58e-34: 139: 14.16		FOXP4_HUMAN (1-669): 0: 599: 100.00
+	Hs
		178937 TOX_HUMAN (1-526): 2.01e-94: 298: 100.00		FOXP2_HUMAN (201-679): 3.18e-130: 402: 58.75
+	Hs
		727803 SOX5_HUMAN (7-363): 8.3e-45: 170: 13.02		FOXP1_HUMAN (1-679): 1.33e-169: 503: 54.38
+	Hs
		727923 SOX6_HUMAN (17-425): 1.1e-37: 149: 11.62		FOXP1_HUMAN (1-679): 1.33e-169: 503: 54.38
+	Hs
		178952 SOX5_HUMAN (7-363): 8.3e-45: 170: 13.02		FOXP2_HUMAN (201-679): 3.18e-130: 402: 58.75
+	Hs
		178995 SOX13_HUMAN (70-398): 1.58e-34: 139: 14.16		FOXP2_HUMAN (201-679): 3.18e-130: 402: 58.75
+	Mm
		1207354 NSD2_MOUSE (8-482): 3.03e-62: 223: 14.60		FOXP3_MOUSE (205-559): 3.57e-88: 284: 36.43
+	Hs
		877708 SSRP1_HUMAN (43-414): 2.19e-60: 213: 16.45		FOXA1_HUMAN (380-670): 9.39e-51: 185: 18.77
+	Hs
		727724 SOX5_HUMAN (7-363): 8.3e-45: 170: 13.02		FOXK1_HUMAN (363-657): 1.5e-47: 180: 23.03
+	Hs
		1318650 HM20B_HUMAN (221-474): 1.31e-42: 156: 20.69		FOXQ1_HUMAN (371-664): 5.99e-47: 172: 17.28
+	Hs
		1318644 HM20A_HUMAN (171-474): 6.73e-39: 147: 14.95		FOXQ1_HUMAN (371-664): 5.99e-47: 172: 17.28
+	Hs
		1021354 HM20A_HUMAN (171-474): 6.73e-39: 147: 14.95		FOXL1_HUMAN (421-654): 3.78e-43: 160: 25.70
+	Dm
		685359 PANG2_DROME (178-494): 1.6e-35: 143: 9.97		CROC_DROME (466-580): 1.79e-41: 160: 33.33
+	Hs
		996639 SSRP1_HUMAN (43-414): 2.19e-60: 213: 16.45		FOXC1_HUMAN (466-543): 4.66e-12: 70.9: 43.37
+	Hs
		727739 SOX5_HUMAN (7-363): 8.3e-45: 170: 13.02		FOXC1_HUMAN (466-543): 4.66e-12: 70.9: 43.37
+	Hs
		727858 SOX6_HUMAN (17-425): 1.1e-37: 149: 11.62		FOXC1_HUMAN (466-543): 4.66e-12: 70.9: 43.37
+	Hs
		1021167 HM20A_HUMAN (171-474): 6.73e-39: 147: 14.95		FOXC1_HUMAN (466-543): 4.66e-12: 70.9: 43.37