Interactor 1: SUN1 (O94901)
SUN domain-containing protein 1 (Protein unc-84 homolog A) (Sad1/unc-84 protein-like 1)
Gene: SUN1

Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.831

The method score is based on:

Property Details
Experiments 22632968, 33393904
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, molecular sieving, comigration in non denaturing gel electrophoresis, anti bait coimmunoprecipitation
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains KASH~Sad1_UNC
Common GO terms GO:0005521 - lamin binding
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm
GO:0007283 - spermatogenesis
GO:0031965 - nuclear membrane
and 3 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 785
Hs

1 8797
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Last updated: 15 Jul 2024